Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells.
Jagannathan S, Shadle SC, Resnick R, Snider L, Tawil RN, van der Maarel SM, Bradley RK, Tapscott SJ
Hum Mol Genet. 2016 Oct 15;25(20):4419-4431. doi: 10.1093/hmg/ddw271.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 99281 | pCW57.1-DUX4-CA | All-in-one lentivector with tet-inducible DUX4 (codon sequences altered) |
| 99282 | pCW57.1-DUX4-WT | All-in-one lentivector with tet-inducible DUX4 (wildetype nucleotide sequence) |