CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo.
Reimer J, Knoess S, Labuhn M, Charpentier EM, Gohring G, Schlegelberger B, Klusmann JH, Heckl D
Haematologica. 2017 Jun 1. pii: haematol.2017.164046. doi: 10.3324/haematol.2017.164046.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 69146 | L40C-CRISPR.EFS.mNeon | Lentiviral CRISPR-Cas9 delivery for SpCas9 and sgRNA (hU6), mNeon coexpression, EFS Promoter driven |
| 69147 | SGL40C.EFS.RFP657 | Advanced lentiviral Vector for sgRNA (hU6 Promoter) delivery with RFP657 expression (EFS Promoter) |
| 69148 | SGL40C-H1.EFS.RFP657 | Advanced lentiviral Vector for sgRNA (H1 Promoter) delivery with RFP657 expression (EFS Promoter) |
| 69212 | L-CRISPR-CTN (MLL-ENL) | Lentiviral CRISPR-Cas9 vector for induction of chromosomal translocations; MLL-ENL,(t[11;19]) |
| 69215 | L-CRISPR-CTN (MLL-ctrl) | Advanced lentiviral CRISPR-Cas9 vector for induction of chromosomal translocations; control, MLL-sgRNA + luciferase-sgRNA |
| 89392 | L40C-CRISPR.EFS.dTomato | Lentiviral CRISPR-Cas9 delivery for sgRNA (hU6), dTomato coexpression, EFS Promoter driven |
| 89393 | L40C-CRISPR.EFS.PAC | Lentiviral CRISPR-Cas9 delivery for SpCas9 and sgRNA (hU6), PAC (Puromycin resistance) coexpression, EFS Promoter driven |
| 89395 | SGL40C.EFS.dTomato | Advanced lentiviral Vector for sgRNA (hU6 Promoter) delivery with dTomato expression (EFS Promoter) |