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Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency.

Ruparelia AA, Oorschot V, Vaz R, Ramm G, Bryson-Richardson RJ
Acta Neuropathol. 2014 Dec;128(6):821-33. doi: 10.1007/s00401-014-1344-5. Epub 2014 Oct 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
98180p3E_BAG3wt-eGFPCodes for full length, GFP tagged, human wildtype Bag3
98181p3E_BAG3P209L-eGFPCodes for full length, GFP tagged mutant Bag3
98182PUC57_BAG3wt-eGFPCodes for full length, GFP tagged, human wildtype Bag3
98183PUC57_BAG3P209L-eGFPCodes for full length, GFP tagged mutant Bag3

Antibodies from Article