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Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38.

Yuasa T, Ohno S, Kehrl JH, Kyriakis JM
J Biol Chem. 1998 Aug 28. 273(35):22681-92. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
21582pCMV5-FLAG-MKK6
21583pCMV5-FLAG-MKK6-K82M

Antibodies from Article