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BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.

Furukawa M, Xiong Y
Mol Cell Biol. 2005 Jan . 25(1):162-71. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
21549pcDNA3-EGFP-C4-Nrf2
21551pDsRed2-Keap1
21552pCDNA3-T7-Keap1
21553pPROEX-HTc-Flag3-Nrf2
21555pCDNA3-Myc3-Nrf2Mammalian expression of human Nrf2 with Myc tag
21590pCDNA3-Myc3-Cul3 delta N41
21591pcDNA3-Myc3-Cul3 H2M/H5M
21593pcDNA3-HA2-Keap1 delta BTB
21594pcDNA3-HA2-Keap1 S3H4

Antibodies from Article