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ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.

Wang B, Krall EB, Aguirre AJ, Kim M, Widlund HR, Doshi MB, Sicinska E, Sulahian R, Goodale A, Cowley GS, Piccioni F, Doench JG, Root DE, Hahn WC
Cell Rep. 2017 Feb 7;18(6):1543-1557. doi: 10.1016/j.celrep.2017.01.031. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
74953PXPR007 sgCIC-1Cas9 + sgCIC-1 with blasticidin selection
74959PXPR007 sgCIC-2Cas9 + sgCIC-2 with blasticidin selection
74960PXPR007 sgGFP-1Cas9 + sgGFP-1 with blasticidin selection
74961PXPR007 sgGFP-2Cas9 + sgGFP-2 with blasticidin selection
74962PXPR007 sgATXN1L-1Cas9 + sgATXN1L-1 with blasticidin selection
74963PXPR007 sgATXN1L-2Cas9 + sgATXN1L-2 with blasticidin selection
74966pXPR_BRD003 sgCIC-1sgCIC-1, puromycin selection
74967pXPR_BRD003 sgCIC-2sgCIC-2, puromycin selection
74968pXPR_BRD003 sgLacZ-1sgLacZ-1, puromycin selection
74969pXPR_BRD003 sgLacZ-2sgLacZ-2, puromycin selection
74970pXPR_BRD003 sgATXN1L-1sgATXN1L-1, puromycin selection
74971pXPR_BRD003 sgATXN1L-2sgATXN1L-2, puromycin selection
74973pLKO.1 shETV1-AshETV1 shRNA
74974pLKO.1 shETV1-BshETV1 shRNA
74975pLKO.1 shETV4-AshETV4 shRNA
74976pLKO.5 shETV4-BshETV4 shRNA
74977pLKO.5 shETV5-AshETV5 shRNA
74978pLKO.1 shETV5-BshETV5 shRNA
74981pLX_TRC311 ETV1Constitutive ETV1 ORF, blasticidin selection
74982pLX_TRC311 ETV4-LConstitutive ETV4 ORF, blasticidin selection
74983pLX_TRC311 ETV4-SConstitutive ETV4 ORF, blasticidin selection
74984pLX_TRC311 ETV5Constitutive ETV5 ORF (codon optimized), blasticidin selection

Antibodies from Article