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VP16 targets an amino-terminal domain of HCF involved in cell cycle progression.

Wilson AC, Freiman RN, Goto H, Nishimoto T, Herr W
Mol Cell Biol. 1997 Oct;17(10):6139-46. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
92320pCGN-HCF-1-N1011N-term 1-1011 of HCF-1 protein
92321pCGN-HCF-1-N450N-term 1-450 of HCF-1 protein
92322pCGN-HCF-1-N1011Δ382-450N-term of HCF-1 protein without amino acids 382-450
92323pCGN-HCF-1-N450-1011N-term 450-1011 of HCF-1 protein
92324pCGN-HCF-1-C600C-term of HCF-1 protein

Antibodies from Article