Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.
Vo BT, Li C, Morgan MA, Theurillat I, Finkelstein D, Wright S, Hyle J, Smith SM, Fan Y, Wang YD, Wu G, Orr BA, Northcott PA, Shilatifard A, Sherr CJ, Roussel MF
Cell Rep. 2017 Mar 21;18(12):2907-2917. doi: 10.1016/j.celrep.2017.02.073.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 91877 | AOI-WT-Cas9-sg-mouse Gfi1-exon4(F2)-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Gfi1 |
| 91879 | AOI-WT-Cas9-sg-mouse Ezh2-E10-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Ezh2 |
| 91880 | AOI-WT-Cas9-sg-mouse Ezh2-E18-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Ezh2 |
| 91881 | AOI-WT-Cas9-sg-mouse Suz12-F1-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Suz12 |
| 91882 | AOI-WT-Cas9-sg-mouse Suz12-F2-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Suz12 |
| 91883 | AOI-WT-Cas9-sg-mouse Gfi1-exon4(F1)-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Gfi1 |
| 91884 | AOI-WT-Cas9-sg-mouse Gfi1-exon5 (F3)-GFP | Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Gfi1 |
| 91885 | MSCV-mouse Ezh2 delta SETdomain-IRES-GFP | Retroviral expression of mouse Ezh2 with a SET domain deletion |
| 91887 | MSCV-mouse Ezh2 Y637S-IRES-GFP | Retroviral expression of mouse Ezh2 with Y637S |
| 91888 | MSCV-human Erbb2-IRES-GFP | Retroviral expression of human Erbb2 |
| 91889 | MSCV-human HoxB4-IRES-YFP | Retroviral expression of human HoxB4 |
| 91890 | MSCV-human Igf2bp2-IRES-GFP | Retroviral expression of human Igfbp2 |
| 91891 | MSCV-mouse Gfi1-IRES-GFP | Retroviral expression of mouse Gfi1 |
| 91892 | pCDH-CMV-mouse Gfi1-GFP | 3rd generation lentiviral expression of mouse Gfi1 |
| 91893 | pT2K-CAGGS-mouse Gfi1-IRES-GFP | Mammalian expression of mouse Gfi1 |