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RAS transformation requires CUX1-dependent repair of oxidative DNA damage.
Ramdzan ZM, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, Davoudi S, Hulea L, Yao L, Karnezis AN, Paquet M, Dankort D, Nepveu A
PLoS Biol. 2014 Mar 11;12(3):e1001807. doi: 10.1371/journal.pbio.1001807. eCollection 2014 Mar.
PubMed

Plasmids from Article

ID Plasmid Purpose
90469pTRIPZ-DoxOn-shCUX1-5150Lentiviral vector expressing a doxycycline-inducible shRNA against human CUX1 sequence starting at 5150 of M74099
100815pTRIPZ shCUX1-5328Lentiviral vector expressing a doxycycline-inducible short hairpin RNA against CUX1 sequence starting at 5328 of M74099

Antibodies from Article