Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients.
Liu ML, Zang T, Zhang CL
Cell Rep. 2016 Jan 5;14(1):115-28. doi: 10.1016/j.celrep.2015.12.018. Epub 2015 Dec 24.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 90214 | pCSC-NGN2-IRES-GFP-T2A-Sox11 | To convert human skin fibroblasts into induced motor neurons (hiMN) in combination with ISL1, LHX3, FGF2 and two small molecules, forskolin and dorsomorphin. |
| 90215 | pCSC-ISL1-T2A-LHX3 | To convert human skin fibroblasts into induced motor neurons (hiMN) in combination with NGN2, Sox11, FGF2 and two small molecules, forskolin and dorsomorphin. |