Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons.

Liu ML, Zang T, Zou Y, Chang JC, Gibson JR, Huber KM, Zhang CL
Nat Commun. 2013;4:2183. doi: 10.1038/ncomms3183. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

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ID	Plasmid	Purpose
90213	pLNCX2-NGN2-IRES-GFP-T2A-Sox11	To convert human skin fibroblasts into induced cholinergic neurons (hiCN) in combination with FGF2 and two small molecules, forskolin and dorsomorphin.
90212	pLNCX2-NGN2-IRES-GFP	To convert human fetal lung fibroblasts into induced cholinergic neurons (hiCN) in combination with two small molecules, forskolin and dorsomorphin.