Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons.
Liu ML, Zang T, Zou Y, Chang JC, Gibson JR, Huber KM, Zhang CL
Nat Commun. 2013;4:2183. doi: 10.1038/ncomms3183.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 90212 | pLNCX2-NGN2-IRES-GFP | To convert human fetal lung fibroblasts into induced cholinergic neurons (hiCN) in combination with two small molecules, forskolin and dorsomorphin. |
| 90213 | pLNCX2-NGN2-IRES-GFP-T2A-Sox11 | To convert human skin fibroblasts into induced cholinergic neurons (hiCN) in combination with FGF2 and two small molecules, forskolin and dorsomorphin. |