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Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

Pop C, Chen YR, Smith B, Bose K, Bobay B, Tripathy A, Franzen S, Clark AC
Biochemistry. 2001 Nov 27;40(47):14224-35. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
90087pET21b-Caspase-3Expresses wild type caspase 3 in bacterial cells
90088pET21b-Caspase-3(C163S)Expresses caspase 3 with C163S to prevent autocatalysis in bacterial cells

Antibodies from Article