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Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.

Mayerle M, Guthrie C
RNA. 2016 May;22(5):793-809. doi: 10.1261/rna.055459.115. Epub 2016 Mar 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
89966pRS313-PRP8complements prp8 genomic deletion
89967pRS313-prp8-S2197FS2197F point mutant
89968pRS313-prp8-H2387PH2387P point mutant
89969pRS313-prp8-R2388GR2388G point mutant
89971pRS314-PRP16Prp16 in a trp backbone complements prp16 genomic deletion
89972pRS314-prp16-1prp16-1 allele in TRP plasmid
89973pRS314-prp16-101prp16-101 allele in TRP plasmid
89974pRS314-prp16-302prp16-302 allele in TRP plasmid

Antibodies from Article