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KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM
Nature. 2017 Feb 15. doi: 10.1038/nature21423. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
87034pRK5-FLAG-SZT2mammalian expression of SZT2
87035pRK5-HA-SZT2mammalian expression of SZT2
87036pRK5-FLAG-SZT2 1-1021mammalian expression of SZT2 fragment
87037pRK5-HA-SZT2 1-1021mammalian expression of SZT2 fragment
87039pRK5-FLAG-SZT2 2241-endmammalian expression of SZT2 fragment
87040pRK5-HA-SZT2 2241-endmammalian expression of SZT2 fragment
87041pRK5-FLAG-KPTNmammalian expression of KPTN
87042pRK5-HA-KPTNmammalian expression of KPTN
87043pRK5-MYC-KPTNmammalian expression of KPTN
87044pRK5-FLAG-ITFG2mammalian expression of ITFG2
87045pRK5-HA-ITFG2mammalian expression of ITFG2
87046pRK5-MYC-ITFG2mammalian expression of ITFG2
87047pRK5-FLAG-C12orf66mammalian expression of C12orf66
87048pRK5-HA-C12orf66mammalian expression of C12orf66
87049plc242-GFP-ITFG2mammalian expression of ITFG2
87050plc242-GFP-WDR24mammalian expression of WDR24
87051plc242-GFP-Nprl2mammalian expression of Nprl2
87052KG371-GFP-miosmammalian expression of mios

Antibodies from Article