Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors.
Labarca C, Nowak MW, Zhang H, Tang L, Deshpande P, Lester HA
Nature. 1995 Aug 10. 376(6540):514-6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 20684 | pBS-AMV-α1L9'S-nAchR | |
| 20685 | pBS-AMV-β1L9'S-nAchR | |
| 20686 | pBS-AMV-γ1L9'S-nAchR | |
| 20687 | pBS-AMV-δ1L9'S-nAchR | |
| 21738 | pBS-AMVpl | |
| 97080 | pBS-AMVpl-β1WT-nAchR | To determine if structural domains are important for nicotinic acetylcholine receptor (nAChr) channel function via dose-response curves from voltage-clamped oocytes to estimate EC50's and Hill Co |
| 97187 | pBS-AMVpl-γWT-nAchR | To determine if structural domains are important for nicotinic acetylcholine receptor (nAChr) channel function via dose-response curves from voltage-clamped oocytes to estimate EC50's and Hill Co |
| 97188 | pBS-AMVpl-δWT-nAchR | To determine if structural domains are important for nicotinic acetylcholine receptor (nAChr) channel function via dose-response curves from voltage-clamped oocytes to estimate EC50's and Hill Co |