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Normalizing translation through 4E-BP prevents mTOR-driven cortical mislamination and ameliorates aberrant neuron integration.

Lin TV, Hsieh L, Kimura T, Malone TJ, Bordey A
Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11330-11335. Epub 2016 Sep 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
194204pCALNL-Rheb(S16H)Cre/LoxP-dependent expression of a constitutively active form of Rheb (S16H). Expression of Cre excises a STOP codon before Rheb(S16H), facilitating expression of a constitutively active form of Rheb.

Antibodies from Article