SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.
Hong X, Liu W, Song R, Shah JJ, Feng X, Tsang CK, Morgan KM, Bunting SF, Inuzuka H, Zheng XF, Shen Z, Sabaawy HE, Liu L, Pine SR
Nucleic Acids Res. 2016 Oct 14;44(18):8855-8869. Epub 2016 Aug 26.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 111455 | pCMV-Tag2-Sox9 T236A | Transient expression of Flag-tagged human Sox9 with T236A mutation |
| 111457 | pCMV-Tag2-Sox9 T240A | Transient expression of Flag-tagged human Sox9 with T240A mutation |
| 111458 | pCMV-Tag2-Sox9 T236A/T240A | Transient expression of Flag-tagged human Sox9 with T236A/T240A mutation |