PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).

Grundy GJ, Polo LM, Zeng Z, Rulten SL, Hoch NC, Paomephan P, Xu Y, Sweet SM, Thorne AW, Oliver AW, Matthews SJ, Pearl LH, Caldecott KW
Nat Commun. 2016 Aug 17;7:12404. doi: 10.1038/ncomms12404. PubMed Article

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