Directed evolution of key residues in fluorescent protein inverses the polarity of voltage sensitivity in the genetically-encoded indicator ArcLight.
Platisa J, Vasan G, Yang A, Pieribone VA
ACS Chem Neurosci. 2017 Jan 3. doi: 10.1021/acschemneuro.6b00234.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 74216 | CMV Marina-T2A-nls-mCherry | genetically-encoded fluorescent voltage indicator |
| 85803 | CMV epArcLight | genetically-encoded fluorescent voltage indicator |
| 85806 | CMV ArcLightCo (Q239)-T2A-nls-mCherry | Genetically encoded voltage sensor ArcLight- codon optimized |
| 85843 | hSyn Marina-T2A-nls-mCherry | genetically-encoded fluorescent voltage indicator |
| 85844 | hSyn ArcLightCo (Q239)-T2A-nls-mCherry | Genetically encoded voltage sensor ArcLight- codon optimized |