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Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics.

Huang Y, Tejero R, Lee VK, Brusco C, Hannah T, Bertucci TB, Junqueira Alves C, Katsyv I, Kluge M, Foty R, Zhang B, Friedel CC, Dai G, Zou H, Friedel RH
Commun Biol. 2021 Jan 29;4(1):145. doi: 10.1038/s42003-021-01667-4. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
86151pX459-sgPLXNB2Cas9/CRISPR plasmid for cut in human PLXNB2 gene exon 3
86152plentiCRISPRv2-sgPLXNB2Lentivirus carrying Cas9/CRISPR for cut in human PLXNB2 gene exon 3
86153plentiCRISPRv2-sgEGFPLentivirus carrying Cas9/CRISPR for cut in GFP (used as control)
86236pENTR223-PLXNB2PLXNB2 full-length human cDNA CDS in gateway entry plasmid
86237pLV-PLXNB2Lentivirus for expression of human Plexin-B2
86238pLV-PLXNB2-dectoLentivirus for expression of human Plexin-B2 with deletion of ectodomain
86239pLV-PLXNB2-dVTDLLentivirus for expression of human Plexin-B2 with deletion of C-terminal VTDL aminoacids
86240pLV-PLXNB2-mRBDLentivirus for expression of human Plexin-B2 with mutant RBD domain
86241pLV-PLXNB2-mGAPLentivirus for expression of human Plexin-B2 with mutant GAP domain

Antibodies from Article