Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP
Nat Chem Biol. 2016 Nov 7. doi: 10.1038/nchembio.2231.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
85739 | CFP-NS1 | expresses CFP-FLAG-tagged NS1 monobody. |