CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations.
Guernet A, Mungamuri SK, Cartier D, Sachidanandam R, Jayaprakash A, Adriouch S, Vezain M, Charbonnier F, Rohkin G, Coutant S, Yao S, Ainani H, Alexandre D, Tournier I, Boyer O, Aaronson SA, Anouar Y, Grumolato L
Mol Cell. 2016 Aug 4;63(3):526-38. doi: 10.1016/j.molcel.2016.06.017. Epub 2016 Jul 21.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 85557 | sgAPC(A) | Expresses sgRNA targeting human APC around codon I1417 |
| 85558 | sgAPC(B) | Expresses sgRNA targeting human APC around codon I1417 |
| 85559 | sgTP53(A) | Expresses sgRNA targeting human TP53 around codon F109 |
| 85560 | sgTP53(B) | Expresses sgRNA targeting human TP53 around codon F109 |
| 85561 | sgTP53(R273) | Expresses sgRNA targeting human TP53 around codon R273 |
| 85562 | sgALK(A) | Expresses sgRNA targeting human ALK around codon F1174 |
| 85563 | sgALK(B) | Expresses sgRNA targeting human ALK around codon F1174 |
| 85564 | sgEGFR(A) | Expresses sgRNA targeting human EGFR around codon T790 |
| 85565 | sgEGFR(B) | Expresses sgRNA targeting human EGFR around codon T790 |
| 85566 | sgKRAS(A) | Expresses sgRNA targeting human KRAS around codon G12 |
| 85567 | sgKRAS(B) | Expresses sgRNA targeting human KRAS around codon G12 |
| 85568 | sgEML4 | Expresses sgRNA targeting human EML4 between exon 13 and 14 |
| 85569 | sgALK(Chr. Inv.) | Expresses sgRNA targeting human ALK between exon 20 and 21 |
| 85570 | sgAAVS1(A) | Expresses sgRNA targeting human AAVS1 locus |
| 85571 | sgAAVS1(B) | Expresses sgRNA targeting human AAVS1 locus |