The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM
Science. 2008 Jun 13. 320(5882):1496-501.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 19298 | pRK5-HA GST RagA wt | |
| 19299 | pRK5-HA GST RagA 21L | |
| 19300 | pRK5-HA GST RagA 66L | |
| 19301 | pRK5-HA GST RagB wt | |
| 19302 | pRK5-HA GST RagB 54L | |
| 19303 | pRK5-HA GST RagB 99L | |
| 19304 | pRK5-HA GST RagC wt | |
| 19305 | pRK5-HA GST RagC 75L | |
| 19306 | pRK5-HA GST RagC 120L | |
| 19307 | pRK5-HA GST RagD wt | |
| 19308 | pRK5-HA GST RagD 77L | |
| 19309 | pRK5-HA GST RagD 121L | |
| 19310 | pRK5-HA GST Rheb1 | |
| 19311 | Flag pLJM1 Rap2A | |
| 19312 | Flag pLJM1 Rheb1 | |
| 19313 | Flag pLJM1 RagB wt | |
| 19314 | Flag pLJM1 RagB 54L | |
| 19315 | Flag pLJM1 RagB 99L | |
| 19316 | Flag pLJM1 RagD wt | |
| 19317 | Flag pLJM1 RagD 77L | |
| 19318 | Flag pLJM1 RagD 121L | |
| 19319 | pLJM1-EGFP | 3rd gen lentiviral vector for EGFP fusion; PGK driven puromycin |
| 26625 | pLKO.1 Rheb1 shRNA #1 | |
| 26626 | pLKO.1 Rheb1 shRNA #2 | |
| 26627 | pLKO.1 RagB shRNA #1 | |
| 26628 | pLKO.1 RagB shRNA #2 | |
| 26629 | pLKO.1 RagC shRNA #1 | |
| 26630 | pLKO.1 RagC shRNA #2 | |
| 30319 | pLKO.1 RagA shRNA #1 | |
| 30320 | pLKO.1 RagA shRNA #2 | |
| 30321 | pLKO.1 RagD shRNA #1 | |
| 30322 | pLKO.1 RagD shRNA #2 | |
| 30323 | pLKO.1 GFP shRNA |