Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration.
O'Neill PR, Kalyanaraman V, Gautam N
Mol Biol Cell. 2016 May 1;27(9):1442-50. doi: 10.1091/mbc.E15-12-0832. Epub 2016 Mar 3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 85220 | ITSN-mcherry-sspB | Role of Cdc-42 selective GEF domain from ITSN in immune cell migration |
| 85221 | mTiam1-mcherry-sspB in pcDNA3.1 | Role of Rac selective GEF domain from Tiam1 in immune cell migration |
| 85222 | Venus wGBD | Venus tagged Cdc-42 sensor |
| 85223 | PH Akt-Venus | Venus tagged PH domain of Akt for use as a PIP3 sensor |
| 85680 | ILID-CAAX | Expression of untagged ILID CAAX |