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Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

Jovicic A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW 3rd, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD
Nat Neurosci. 2015 Sep;18(9):1226-9. doi: 10.1038/nn.4085. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
84901pAG416-Gal-PR50induce expression of dipeptide repeat PR in yeast
84902pAG416-Gal-PA50induce expression of dipeptide repeat PA in yeast
84903pAG416-Gal-GA50induce expression of dipeptide repeat GA in yeast
84905pAG303-Gal-PR50induce expression of dipeptide repeat PR in yeast
84906pAG303-Gal-PA50induce expression of dipeptide repeat PA in yeast
84907pAG303-Gal-GA50induce expression of dipeptide repeat GA in yeast
84908pAG303-Gal-GR100induce expression of dipeptide repeat GR in yeast

Antibodies from Article