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SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition.

Kim E, Ilagan JO, Liang Y, Daubner GM, Lee SC, Ramakrishnan A, Li Y, Chung YR, Micol JB, Murphy ME, Cho H, Kim MK, Zebari AS, Aumann S, Park CY, Buonamici S, Smith PG, Deeg HJ, Lobry C, Aifantis I, Modis Y, Allain FH, Halene S, Bradley RK, Abdel-Wahab O
Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
84014pUB6_EZH2EZH2 minigene to test splicing event
84020pRRL_SRSF2_WT_mCherryexpression of SRSF2 in mammalian cells
84021pRRL_SRSF2_P95R_mCherryexpression of SRSF2 mutant in mammalian cells
84022pRRL_SRSF2_P95L_mCherryexpression of SRSF2 mutant in mammalian cells
84023pRRL_SRSF2_P95H_mCherryexpression of SRSF2 mutant in mammalian cells

Antibodies from Article