C9orf72 binds SMCR8, localizes to lysosomes and regulates mTORC1 signaling.
Amick J, Roczniak-Ferguson A, Ferguson SM
Mol Biol Cell. 2016 Aug 24. pii: mbc.E16-01-0003.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 83437 | pEGFP-C9orf72 | Expresses GFP-C9orf72 in mammalian cells |
| 83438 | ptdTomato-SMCR8 | Expresses SMCR8-tdTomato in mammalian cells |
| 83439 | pSpCas9(BB)-2A-Puro-C9orf72 | Expresses Cas9 and a gRNA targeting C9orf72 |
| 83440 | pSpCas9(BB)-2A-Puro-SMCR8 | Expresses Cas9 and a gRNA targeting SMCR8 |