N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain.
Raikwar NS, Liu KZ, Thomas CP
PLoS One. 2014 Nov 11;9(11):e112794. doi: 10.1371/journal.pone.0112794. eCollection 2014.
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PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 86036 | hFLT1 delta CTD | human VEGFR1 with deletion of the entire intracellular domain |
| 86037 | hFlt1 Y1333F | human VEGFR1 with Y to F mutation at position 1333 |