A novel cytoprotective function for the DNA repair protein Ku in regulating p53 mRNA translation and function.
Lamaa A, Le Bras M, Skuli N, Britton S, Frit P, Calsou P, Prats H, Cammas A, Millevoi S
EMBO Rep. 2016 Apr;17(4):508-18. doi: 10.15252/embr.201541181. Epub 2016 Mar 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 82329 | pICE-HA-Ku70-siR-WT | Plasmid for constitutive or doxycycline-inducible expression of wild-type human Ku70 resistant to a siRNA. Confers resistance to puromycin. Use T-REx cells for doxycycline-inducible expression. |
| 82330 | pICE-HA-Ku70-siR-Mut6E | Plasmid for constitutive or doxy-inducible expression of mutant human Ku70 unable to bind DNA and resistant to siRNA. Confers resistance to puro. Use T-REx cells for doxycycline-inducible expression. |