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The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.

Raja E, Tzavlaki K, Vuilleumier R, Edlund K, Kahata K, Zieba A, Moren A, Watanabe Y, Voytyuk I, Botling J, Soderberg O, Micke P, Pyrowolakis G, Heldin CH, Moustakas A
Oncotarget. 2016 Jan 12;7(2):1120-43. doi: 10.18632/oncotarget.6683. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
80870pcDNA3-ALK2 wtmammalian expression of ALK2 WT
80871pcDNA3-ALK2 Q207Dmammalian expression of ALK2 Q207D
80872pcDNA3-ALK2 K235Rmammalian expression of ALK2 K235R
80873pcDNA3-ALK3 wtmammalian expression of ALK3 WT
80874pcDNA3-ALK3 Q233Dmammalian expression of ALK3 Q233D
80875pcDNA3-ALK3 K261Rmammalian expression of ALK3 K261R
80882pcDNA3-ALK6 wtmammalian expression of ALK6 WT
80883pcDNA3-ALK6 Q203Dmammalian expression of ALK6 Q203D
80884pcDNA3-ALK6 K231Rmammalian expression of ALK6 K231R

Antibodies from Article