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Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability.

Pattabiraman DR, Bierie B, Kober KI, Thiru P, Krall JA, Zill C, Reinhardt F, Tam WL, Weinberg RA
Science. 2016 Mar 4;351(6277):aad3680. doi: 10.1126/science.aad3680. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
91700pLIX402 PHF2inducible lentiviral expression of PHF2
91701pLIX402 caPHF2inducible lentiviral expression of constitutively active PHF2
917037TFP CDH1 mutant reporterlentiviral luciferase reporter containing CDH1 promoter with mutant E-boxes
917047TFP CDH1 reporterlentiviral luciferase reporter containing CDH1 promoter

Antibodies from Article