A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level.
Erapaneedi R, Belousov VV, Schafers M, Kiefer F
EMBO J. 2016 Jan 4;35(1):102-13. doi: 10.15252/embj.201592775. Epub 2015 Nov 23.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
201710 | HRE-UnaG | Hypoxia responsive promoter driving UnaG fluorescent proteins |
201711 | HRE-dUnaG | Hypoxia responsive promoter driving destablized UnaG fluorescent protein |
201712 | HRE-oUnaG | Hypoxia responsive promoter driving UnaG fluorescent protein destablized using ODDD fragment from HIF1a |
201713 | HRE-doUnaG | Hypoxia responsive promoter driving UnaG fluorescent protein destablized using ODDD fragment from HIF1a and a PEST sequence |
201714 | HRE-dUnOHR | Hypoxia responsive promoter driving UnaG and mOrange |