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BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment.

Toledo CM, Herman JA, Olsen JB, Ding Y, Corrin P, Girard EJ, Olson JM, Emili A, DeLuca JG, Paddison PJ
Dev Cell. 2014 Feb 10;28(3):282-94. doi: 10.1016/j.devcel.2013.12.014. Epub 2014 Jan 23. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
84024GUT BuGZ FLExpression of GFP tagged BuGZ in human cells
84025GUT BuGZ delta ZF1Expression of GFP tagged mutant BuGZ in human cells
84026GUT BuGZ delta ZF2Expression of GFP tagged mutant BuGZ in human cells
84027GUT BuGZ delta ZF1, delta ZF2Expression of GFP tagged mutant BuGZ in human cells
84028GUT BuGZ delta GLEBSExpression of GFP tagged mutant BuGZ in human cells
84029GUM BUB3Expression of mCherry tagged BUB3 in human cells

Antibodies from Article