Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.

Neagu MR, Ziegler P, Pertel T, Strambio-De-Castillia C, Grutter C, Martinetti G, Mazzucchelli L, Grutter M, Manz MG, Luban J
J Clin Invest. 2009 Oct;119(10):3035-47. doi: 10.1172/JCI39354. Epub 2009 Sep 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

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ID	Plasmid	Purpose
80282	pFUPI hT5-S322-Cyp	Expresses human TRIM5 CypA fusion
80281	pFUPI hT5Cyp-H126Q	Expresses human TRIM5 CypA fusion with H126Q mutation in CypA
80280	pFUPI AoT5Cyp	Expresses Aotus TRIM5 CypA fusion
80279	pFUPI	A bicistronic lentiviral vector used to stably express cDNAs.