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CUP promotes deadenylation and inhibits decapping of mRNA targets.

Igreja C, Izaurralde E
Genes Dev. 2011 Sep 15;25(18):1955-67. doi: 10.1101/gad.17136311. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
146028pAc5.1B-EGFP-DmCup_1-417-V5His6_CInsect Expression of DmCup_1-417
146029pAc5.1B-EGFP-DmCup_419-771-V5His6_CInsect Expression of DmCup_419-771
146030pAc5.1B-EGFP-DmCup_771-1132_CInsect Expression of DmCup_771-1132
146031pAc5.1B-lambdaN-HA-DmCup-4Ala-mut_CInsect Expression of DmCup-4Ala-mut
146032pAc5.1B-lambdaN-HA-DmCup_1-417-V5His6_CInsect Expression of DmCup_1-417
146033pAc5.1B-lambdaN-HA-DmCup_419-771-V5His6_CInsect Expression of DmCup_419-771
146034pAc5.1B-lambdaN-HA-DmCup_771-1132_CInsect Expression of DmCup_771-1132
146035pAc5.1B-lambdaN-HA-DmCup-Y342AL347A_CInsect Expression of DmCup-Y342AL347A
146689pAc5.1A-DmDCP2-E361Q-dsRNAres-V5His6_JInsect Expression of DmDCP2-E361Q-dsRNAres
146891pAc5.1-Dm7SL-RNA-long_MInsect Expression of Dm7SL-RNA-long
146892pAc5.1-Dm7SL-RNA-short_MInsect Expression of Dm7SL-RNA-short
146895pAc5.1B-lambdaN-HA-DmCup_1-417_MInsect Expression of DmCup_1-417
146896pAc5.1B-lambdaN-HA-DmCup_1-417-4Ala-mut_MInsect Expression of DmCup_1-417-4Ala-mut
146897pAc5.1B-lambdaN-HA-DmCup_1-417-4Ala-mut-V5His6_MInsect Expression of DmCup_1-417-4Ala-mut
146898pAc5.1B-lambdaN-HA-DmCup_1-417-L379AL383A_MInsect Expression of DmCup_1-417-L379AL383A
146899pAc5.1B-lambdaN-HA-DmCup_1-417-L379AL383A-V5His6_MInsect Expression of DmCup_1-417-L379AL383A
146900pAc5.1B-lambdaN-HA-DmCup_1-417-Y342AL347A_MInsect Expression of DmCup_1-417-Y342AL347A
146901pAc5.1B-lambdaN-HA-DmCup_1-417-Y342AL347A-V5His6_MInsect Expression of DmCup_1-417-Y342AL347A
146902pAc5.1B-lambdaN-HA-DmCup_1-779_MInsect Expression of DmCup_1-779
146903pAc5.1B-lambdaN-HA-DmCup_1-779-4Ala-mut_MInsect Expression of DmCup_1-779-4Ala-mut
146904pAc5.1B-lambdaN-HA-DmCup_1-779-L379AL383A_MInsect Expression of DmCup_1-779-L379AL383A
146905pAc5.1B-lambdaN-HA-DmCup_1-779-Y342AL347A_MInsect Expression of DmCup_1-779-Y342AL347A
146906pAc5.1B-lambdaN-HA-DmCup_418-1132_MInsect Expression of DmCup_418-1132
146907pAc5.1B-lambdaN-HA-DmCup-del419-770_MInsect Expression of DmCup-del419-770
146908pAc5.1B-lambdaN-HA-DmCup-del419-770-4Ala-mut_MInsect Expression of DmCup-del419-770-4Alal-mut
146909pAc5.1B-lambdaN-HA-DmCup-del419-770-L379AL383A_MInsect Expression of DmCup-del419-770-L379AL383A
146910pAc5.1B-lambdaN-HA-DmCup-del419-770-Y342AL347A_MInsect Expression of DmCup-del419-770-Y342AL347A
146911pAc5.1B-lambdaN-HA-DmCup-del580-600_MInsect Expression of DmCup-del580-600
146912pAc5.1B-lambdaN-HA-DmCup-L379AL383A_MInsect Expression of DmCup-L379AL383A
146913pGEX-CS-DmCup_311-440_MBacterial Expression of DmCup_311-440
146914pGEX-CS-DmCup_311-440-4Ala-mut_MBacterial Expression of DmCup_311-440-4Ala-mut
146916pGEX-CS-DmCup_311-440-Y342AL347A_MBacterial Expression of DmCup_311-440-Y342AL347A
147027pAc5.1A-DmXRN1-dsRNAres-V5His6_NInsect Expression of DmXRN1-dsRNAres
147028pAc5.1B-EGFP-DmBruno_NInsect Expression of DmBruno
147029pAc5.1B-EGFP-DmNot1-dsRNAres_NInsect Expression of DmNot1-dsRNAres
147030pAc5.1B-lambdaN-HA-DmBruno_NInsect Expression of DmBruno

Antibodies from Article