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Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response.

Lee MS, Seo J, Choi DY, Lee EW, Ko A, Ha NC, Yoon JB, Lee HW, Kim KP, Song J
Cell Death Differ. 2013 Apr;20(4):620-9. doi: 10.1038/cdd.2012.159. Epub 2012 Dec 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
78780pCS3-MT-BX-6MYC p21To overexpress p21 in Mammalian Cells
78782pcDNA3-HA p21To overexpress p21 in Mammalian Cell
78783pBABE-puro p21Retroviral expression of p21
78784pCS3-MT-BX-6MYC p21 1-89To overexpress p21 1-89 in Mammalian Cells
78785pCS3-MT-BX-6MYC p21 90-139To overexpress p21 90-139 in Mammalian Cells
78786pCS3-MT-BX-6MYC p21 90-164To overexpress p21 90-164 in Mammalian Cell
78787pcDNA3-HA p21 K163RTo overexpress p21 K163R in Mammalian Cells
78788pcDNA3-HA p21 K161RTo overexpress p21 K161R in Mammalian Cells
78789pcDNA3-HA p21 K161R, K163RTo overexpress p21 K161R, K163R in Mammalian Cells
78790pcDNA3-HA p21 K161Q, K163QTo overexpress p21 K161Q, K163Q in Mammalian Cells
78791pBABE-puro p21 K161R, K163RRetroviral expression of p21 K161R, K163R
78792pBABE-puro p21 K161Q, K163QRetroviral expression of p21 K161Q, K163Q
78793p3xFLAG-CMV TIP60 delta HATTo overexpress TIP60 delta HAT in Mammalian Cell
78794p3xFLAG-CMV TIP60 1-211To overexpress TIP60 1-211 in Mammalian Cells
78795p3xFLAG-CMV TIP60 212-364To overexpress TIP60 212-364 in Mammalian Cells
78796p3xFLAG-CMV TIP60 365-513To overexpress TIP60 365-513 in Mammalian Cells
78797p3xFLAG-CMV TIP60 390-513To overexpress TIP60 390-513 in Mammalian Cells

Antibodies from Article