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A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype.

Nicolaides NC, Littman SJ, Modrich P, Kinzler KW, Vogelstein B
Mol Cell Biol. 1998 Mar . 18(3):1635-41. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
16475pSG5 PMS2-wt
16476pSG5 PMS2-134
16627pCAR-OF reporter
16628pCAR-IF reporter

Antibodies from Article