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Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio.

Titov DV, Cracan V, Goodman RP, Peng J, Grabarek Z, Mootha VK
Science. 2016 Apr 8;352(6282):231-5. doi: 10.1126/science.aad4017. Epub 2016 Apr 7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
74448pUC57-mitoLbNOXThis plasmid contains human codon optimized sequence of mitoLbNOX which is a water-forming NADH oxidase that can be used to increase NAD+/NADH ratio in mammalian cells.
75285pUC57-LbNOXThis plasmid contains human codon optimized sequence of LbNOX which is a water-forming NADH oxidase that can be used to increase NAD+/NADH ratio in mammalian cells.

Antibodies from Article