FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.
Kazi JU, Ronnstrand L
Mol Oncol. 2013 Jun;7(3):402-18. doi: 10.1016/j.molonc.2012.11.003. Epub 2012 Nov 29.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
74501 | pcDNA3-FLAG-Grb10-WT | Overexpression of Grb10 in mammalian cells |