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The Treacher Collins syndrome (TCOF1) gene product, treacle, is targeted to the nucleolus by signals in its C-terminus.

Winokur ST, Shiang R
Hum Mol Genet. 1998 Nov;7(12):1947-52. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
74296CΔ1Mammalian expression of treacle (residues 1176-1302) fused to GFP
74297CΔ2Mammalian expression of treacle (residues 1176-1270) fused to GFP
74298CΔ3Mammalian expression of treacle (residues 1262-1302) fused to GFP
74299CΔ4Mammalian expression of treacle (residues 1271-1302) fused to GFP
74300NRCoCMammalian expression of full-length treacle fused to GFP

Antibodies from Article