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Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain.

Bryan NB, Dorfleutner A, Rojanasakul Y, Stehlik C
J Immunol. 2009 Mar 1;182(5):3173-82. doi: 10.4049/jimmunol.0802367. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
73952pcDNA3-Myc-ASCExpress c-Myc-tagged human ASC in mammalian cells
73953pCMV-pro-IL1bExpress murine pro-interleukin-1 beta in mammalian cells

Antibodies from Article