Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M
Elife. 2016 Jan 26;5. pii: e12245. doi: 10.7554/eLife.12245.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 111803 | pLU-CMV-Flag-hATG5 WT | Mammalian Expression of hATG5 |
| 111804 | pLU-CMV-Flag-hATG5 E122D | Mammalian Expression of hATG5 |
| 166851 | pRS416 ATG5-E141D-HA-ATG12-ATG16 | Expresses mutant E141D ATG5, HA-ATG12 ATG16 in yeast. |