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TRIM5alpha degradation via autophagy is not required for retroviral restriction.

Imam S, Talley S, Nelson RS, Dharan A, O'Connor C, Hope TJ, Campbell EM
J Virol. 2016 Jan 13. pii: JVI.03033-15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
99573LentiCRISPRv2-ATG5Expresses Cas9 with sgRNA targeting Exon 7 of ATG5
99574LentiCRISPRv2-Beclin1Expressed Cas9 with sgRNA targeting Beclin1

Antibodies from Article