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HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase beta.

Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW
Nat Commun. 2014 Nov 26;5:5513. doi: 10.1038/ncomms6513. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
128652pLVX-EGFP-IRES-puromammalian expression of EGFP with puromycin selection
128653pLVX-Flag-Polß(WT)-IRES-puromammalian expression of Flag-Polß(WT) protein with puromycin selection
128654pLVX-Flag-Polß(L301R)-IRES-puromammalian expression of Flag-Polß(L301R) protein with puromycin selection
128655pLVX-Flag-Polß(V306R)-IRES-puromammalian expression of Flag-Polß(V306R) protein with puromycin selection
128656pLVX-Flag-Polß(L301R/V306R)-IRES-puromammalian expression of Flag-Polß(L301R/V306R) with puromycin selection
128657pLVX-Flag-Polß(L301R/V303R/V306R)-IRES-puromammalian expression of Flag-Polß(L301R/V303R/V306R) protein with puromycin selection
128658pLVX-Flag-Polß(L301R/V303R)-IRES-puromammalian expression of Flag-Polß(L301R/V303R) protein with puromycin selection
128659pLVX-Flag-Polß(V303R)-IRES-puromammalian expression of Flag-Polß(V303R) protein with puromycin selection
128660pLVX-EGFP-IRES-Neomammalian expression of EGFP with neomycin selection
128661pLVX-Flag-Polß(K72A)-IRES-puromammalian expression of Flag-Polß(K72A) protein with puromycin selection
128663pLVX-Flag-Polß(WT)-IRES-Neomammalian expression of Flag-Polß(WT) protein with neomycin selection
128664pLVX-Flag-Polß(L301R/V303R)-IRES-neomammalian expression of Flag-Polß(L301R/V303R) protein with neomycin selection
128665pCT-CMV-copGFP-Polß(WT)-puromammalian expression of copGFP-Polß(WT) protein with puromycin selection
128666pCT-CMV-copGFP-Polß(L301R/V303R/V306R)-puromammalian expression of copGFP-Polß(L301R/V303R/V306R: TM) protein with puromcyin selection
128667pLVX-Flag-Polß(WT)--IRES-hygmammalian expression of Flag-Polß(WT) protein with hygromycin selection
128668pLVX-Flag-Polß(TM)-IRES-hygmammalian expression of Flag-Polß(TM: L301R/V303R/V306R) protein with hygromycin selection
128670pLVX-Flag-Polß(KTM)-IRES-Neomammalian expression of Flag-Polß(KTM: K41R/K61R/K81R) protein with neomycin selection
128671pLVX-Flag-Polß(TM)-IRES-neomammalian expression of Flag-Polß(TM: L301R/V303R/V306R) protein with neomycin selection
128672pLVX-Flag-Polß(KTM)-IRES-puromammalian expression of Flag-Polß(KTM: K41R/K61R/K81R) protein with puromycin selection
128675pLVX-Flag-Polß(TM-KTM)-IRES-neomammalian expression of Flag-Polß(TM-KTM: L301R/V303R/V306R-K41R/K61R/K81R) protein with neomycin selection
128676pLVX-Flag-Polß(TM-KTM)-IRES-puromammalian expression of Flag-Polß(TM-KTM: L301R/V303R/V306R-K41R/K61R/K81R) protein with puromycin selection
128677pLVX-Flag-Polß(D256A)-IRES-puromammalian expression of Flag-Polß(D256A) protein with puromycin selection
128678pLVX-Flag-Polß(K206A)-IRES-puromammalian expression of Flag-Polß(K206A) protein with puromycin selection
128679pLVX-Flag-Polß(TM-K206A)-IRES-puromammalian expression of Flag-Polß(TM-K206A: L301R/V303R/V306R-K206A) protein with puromycin slection
128680pLVX-Flag-Polß(TM-K244A)-IRES-puromammalian expression of Flag-Polß(TM-K244A: L301R/V303R/V306R-K244A) portein with puromycin selection
128682pLVX-Flag-Polß(K244A)-IRES-puromammalian expression of Flag-Polß(K244A) protein with puromycin selection
128683pLVX-Flag-Polß(K206A/K244A)-IRES-puromammalian expression of Flag-Polß(K206A/K244A) protein with puromycin selection
128684pLVX-Flag-Polß(TM/K206A/K244A)-IRES-puromammalian expression of Flag-Polß(TM/K206A/K244A: L301R/V303R/V306R/K206A/K244A)) protein with puromycin selection

Antibodies from Article