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Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.

Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J
Curr Biol. 2003 Aug 5. 13(15):1259-68. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
15888pRK7-Rheb
15889pGEX-4T2-Rheb

Antibodies from Article