XPLN is an endogenous inhibitor of mTORC2.
Khanna N, Fang Y, Yoon MS, Chen J
Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15979-84. doi: 10.1073/pnas.1310434110. Epub 2013 Sep 16.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 73376 | pCMV-Myc-XPLN-L269E | Mammalian expression of mutant XPLN (Arhgef3) gene Leu269 --> Glu |
| 73377 | pCMV-Myc-XPLN-W440L | Myc tagged human XPLN expression with a point mutation W440L |
| 73378 | pCMV-Myc-XPLN aa1-125 (N125) | Expression of the N-terminal region of XPLN (amino acids 1–125, designated N125) |
| 73379 | pCMV-Myc-XPLN aa107-311 | Expresses amino acids 107-317 of XPLN (Arhgef3) protein |
| 73380 | pCMV-Myc-XPLN aa304-466 (PH) | Expresses amino acids 304-466 of XPLN (Arhgef3) protein |
| 73381 | pCMV-Myc-XPLN aa452-526 | Expresses amino acids 452-526 of XPLN (Arhgef3) protein |
| 73382 | pCMV-Myc-XPLN (delta)N (aa1-117 deleted) | Expresses myc tagged XPLN in mammalian cells with deletion of N-terminal amino acids 1-117 |