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A mechanism for the suppression of homologous recombination in G1 cells.

Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, Sherker A, Munro M, Pinder J, Salsman J, Dellaire G, Xia B, Peter M, Durocher D
Nature. 2015 Dec 9. doi: 10.1038/nature16142. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
71107pDEST-FRT-TO-GFP-PALB2 KRmammalian expression of GFP-PALB2 mutant. (first 8 Lysine residues mutated to Arginine)
71108pCW-Flag-CtIPmammalian expession of Flag-CtlP
71109pCW-GFP-CtIPmammalian expession of GFP-CtlP
71110pCW-Flag-CtIP-T847Emammalian expession of Flag-CtlP T847E mutation
71111pCW-GFP-CtIP-T847Emammalian expession of GFP-CtlP T847E mutation
71112pDEST-mCherry-LacR-PALB2mammalian expession of mCherry-LacR-PALB2
71113pDEST-FRT/T0-GFP-PALB2mammalian expession of GFP-PALB2
71114pDEST-FRT/T0-Flag-PALB2mammalian expession of FLAG-PALB2
71115pDEST-mCherry-LacR-BRCA1mammalian expression of mCherry-LacR-BRCA1 siRNA resistant construct
71116pDEST-FRT/T0-GFP-BRCA1mammalian expression of GFP-BRCA1 siRNA resistant construct
71117pDEST-FRT/T0-Flag-BRCA1mammalian expression of Flag-BRCA1 siRNA resistant construct
71118pDEST-mCherry-LacR-BRCA1 1366-1437mammalian expession of mCherry-LacR-BRCA1 1366-1437
71119pDEST-FRT/T0-GFP-BRCA1 1364-1437Mammalian expression of GFP-BRCA1 1364-1437

Antibodies from Article