Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA
Nat Methods. 2015 Dec;12(12):1143-9. doi: 10.1038/nmeth.3630. Epub 2015 Oct 26.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 71236 | pLV hU6-sgRNA hUbC-dCas9-KRAB-T2a-Puro | Express sgRNA and dCas9-KRAB from lentiviral vector |
| 71237 | pLV hU6-sgRNA hUbC-dCas9-KRAB-T2a-GFP | Express sgRNA and dCas9-KRAB from 3rd generation lentiviral vector |