The C-terminal proteolytic fragment of the breast cancer susceptibility type 1 protein (BRCA1) is degraded by the N-end rule pathway.
Xu Z, Payoe R, Fahlman RP
J Biol Chem. 2012 Mar 2;287(10):7495-502. doi: 10.1074/jbc.M111.301002. Epub 2012 Jan 18.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 78960 | RF-118-UB-BRCA1 | Expression of the C-terminal fragment of BRCA1 that is endogenously generated by caspase cleavage in mammalian cells |