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EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.

Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, Du Y, Wang Y, Chang WC, Chen CH, Hsu JL, Wu Y, Lam YC, James BP, Liu X, Liu CG, Patel DJ, Hung MC
Nature. 2013 May 16;497(7449):383-7. doi: 10.1038/nature12080. Epub 2013 May 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
71870pMIR-21 ReporterMammalian expression vector for the analysis of miR-21 activity
71871pMIR-31-ReporterMammalian expression vector for the analysis of miR-31 activity
71872pMIR-192-ReporterMammalian expression vector for the analysis of miR-19α activity
71873pMIR-193a-5p-ReporterMammalian expression vector for the analysis of miR-193a-5p activity
71874pMIR-31-192-193a-ReporterMammalian expression vector for the analysis of miR-31-19α-193a activity
72207pCMV5-Flag-Ago2Mammalian expression of full-length human Ago2
72208pCMV5-Flag-Ago2-FDM1Mammalian expression of aa 1-372 of human Ago2
72209pCMV5-Flag-Ago2-FDM2Mammalian expression of aa 1-517 of human Ago2
72210pCMV5-Flag-Ago2-FDM3Mammalian expression of aa 227-860 of human Ago2
72211pCMV5-Flag-Ago2-FDM4Mammalian expression of aa 373-860 of human Ago2
72212pCMV5-Flag-Ago2-FDM5Mammalian expression of aa 518-860 of human Ago2

Antibodies from Article